The widely recognised transition to e-Work brought by recent advances in Internet technology, Web intelligence, virtual social networks and the emerging knowledge economy has necessitated a “rethinking” of our collaborative working environments, and created a renewed need for intelligent Computer-Supported Collaborative Work. Emerging models of distributed virtual projects, namely e-Science, e-Business, e-Health, e-Governance and rural e-Services require creative and adaptive environments that will offer appropriate on-demand knowledge to augment workers’capabilities, and semantically facilitate natural interactions among e-Workers (humans, machines and applications) during collaborative problem-solving and decision-making.